Denver Broncos vs. Buffalo Bills Picks, Odds & Betting Trends - Jan 12, 2025

FULL GAME 1ST HALF FIRST QUARTER 2ND HALF
1:00 PM EST SPREAD MONEYLINE TOTAL
Denver Broncos +7.5 (-105) +365 arrow 49 (-115)
Buffalo Bills -7.5 (-115) -455 arrow 49 (-105)
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Denver Broncos vs. Buffalo Bills Score, Odds and Line Movement

Denver Broncos

7

Buffalo Bills

31

SPREAD

Denver Broncos
49 20%
Buffalo Bills
194 80%

TOTAL

Over
85 91%
Under
8 9%

Denver Broncos vs. Buffalo Bills Game Preview

Football Preview - 01-12-2025 The seventh-seeded Denver Broncos travel to Highmark Stadium to face off with the second-seeded Buffalo Bills in a Wild Card matchup. While Buffalo has had regular-season success, reaching five straight playoff appearances without progressing beyond divisional round, this could finally be their year to break through and reach post-divisional rounds.

Rookie quarterback Bo Nix has led his team to impressive results this year, yet now faces an experienced playoff squad looking for any potential mistakes that he might make.

Denver and Buffalo enter this game healthy. Buffalo's secondary is starting to come together following the return of safety Jordan Poyer and slot corner Taron Johnson; this could limit how often big plays against Denver's pass defense occur for Buffalo.

Denver's passing attack has been one of the season's more effective ones. Courtland Sutton has emerged as a key target, making him an excellent matchup against a Bills defense that has shown some weakness against high-powered offenses. Expect the Broncos to use an attacking mix of short and intermediate passes.

The Buffalo Bills are an impressive team in their own right, but will struggle against the spread in this matchup. While their defense will keep this game close throughout, too few points will be scored against an explosive Denver offense capable of producing multiple scores at will.

If you are looking to make best NFL picks? But if you're not sure who to take, why not check out free NFL betting splits where you can see where the public is betting. You can either choose to fade the public or ride with them. The choice is yours. If you are looking for more options when it comes to making your picks, you can always check out NFL AI generated picks. These computer picks are updated weekly with the latest information.

These picks may change as we get more data. (computer pick in orange)

Spread Pick: Denver Broncos +7.5

Total Pick: arrow 49

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